modelAcetaminophenEquations
Information
Simple equation based model with pharmacokinetic parameter of acetaminophen (paracetamol) [1].
[1] https://sepia2.unil.ch/pharmacology/drugs/paracetamol/
Parameters
| Type | Name | Default | Description |
|---|---|---|---|
| Real | F | 0.8 | bioavailability |
| Real | Dose | 1000*1e-6 | dose |
| Real | Vd | 65*1e-3 | Volume of distribution L/kg to m3/kg |
| Real | Cl | 20*1e-3/3600 | clearance from L/h to m3/s |
| Real | t0 | 60 | time of administration of first dose |
Components
| Type | Name | Default | Description |
|---|---|---|---|
| Pharmacolibrary.Types.MassConcentration | C | concentration | |
| Real | H | heaviside step function | |
| Real | effectiveDose | dose that is effectively absorbed | |
| Real | eliminationRate | rate the drug is cleared from | |
| Real | ammountDrug | ammount of the drug administered | |
| Real | halfLife | half life of the drug |