modelSingleDoseIVAmiodarone
Extends from Modelica.Icons.Example (Icon for runnable examples).
Information
TheSingleDoseIVAmiodaronePK model is concrete example of IV dose of a drug, distribution throughout the veins arteries and tissues with limited elimination.
Amiodarone is an antiarrhythmic medication used to treat and prevent a number of types of cardiac dysrhythmias.
Amiodarone half-life is 40 or more days so elimination rate is very small.
[1] Holt, David W., et al. "Amiodarone pharmacokinetics." American heart journal 106.4 (1983): 840-847.
Components
| Type | Name | Default | Description |
|---|---|---|---|
| Pharmacokinetic.TissueCompartment | tissue | ||
| Pharmacokinetic.SystemicCompartment | arteries | ||
| Pharmacokinetic.SystemicCompartment | veins | ||
| Pharmacokinetic.FixedFlow | fixedFlow | ||
| Sources.SingleDose | singleDose | ||
| Pharmacokinetic.FlowGround | fground | ||
| Pharmacokinetic.ClearanceDrivenElimination | kidneyElim |