modelSystemicCompartment
Systemic compartment
Extends from Pharmacolibrary.Pharmacokinetic.GenericTissueCompartment, Pharmacolibrary.Icons.BloodPlasma.
Information
SystemicCompartment
Systemic compartment is same as TissueCompartment, but the kTB is always 1, so that the concentration in tissue is not considered and is always same as blood/plasma concentration.
Parameters
| Type | Name | Default | Description |
|---|---|---|---|
| Types.Volume | V (from PartialBloodTissueCompartment) | 0.001 | total distribution volume |
| Types.MassConcentration | C0 (from PartialBloodTissueCompartment) | 0 | drug initial concentration in tissue |
| Modelica.Units.SI.DimensionlessRatio | kTB (from PartialBloodTissueCompartment) | 1 | tissue-blood concentration ratio |
| Modelica.Units.SI.DimensionlessRatio | fu (from PartialBloodTissueCompartment) | 1 | fraction unbound |
Connectors
| Type | Name | Default | Description |
|---|---|---|---|
| ConcentrationPort_a | cport (from InterfaceCompartment) | ||
| Pharmacolibrary.Interfaces.FlowPort_a | port_a (from PartialTwoPort) | ||
| Pharmacolibrary.Interfaces.FlowPort_b | port_b (from PartialTwoPort) |
Components
| Type | Name | Default | Description |
|---|---|---|---|
| Types.MassConcentration | C (from PartialBloodTissueCompartment) | drug actual concentration in tissue | |
| Types.MassConcentration | CB (from PartialBloodTissueCompartment) | drug concentration in blood or plasma | |
| Types.MassConcentration | freeTissueConc (from PartialBloodTissueCompartment) | drug free concentration in tissue | |
| Types.MassConcentration | freeBloodConc (from PartialBloodTissueCompartment) | drug free concentration in blood or plasma | |
| Types.Mass | M (from PartialBloodTissueCompartment) | drug mass total | |
| Types.AreaUnderCurve | AUC (from PartialBloodTissueCompartment) | area under curve |