modelOthers
Extends from Pharmacolibrary.Drugs.ATC.D.D11AC30.
Information
| name: | Others | |
| ATC code: | D11AC30 | route: |
| compartments: | 1 | |
| dosage: | 1 | mg |
| volume of distribution: | 1 | L |
| clearance: | 0 | |
| other parameters in model implementation | ||
D11AC30 is an ATC code for 'others' within the class of 'Other dermatologicals - other preparations for treatment of wounds and ulcers.' It is not attributable to a specific chemical entity or widely recognized therapeutic agent. Drugs under this catch-all classification are typically used topically for dermatological use, for wound healing, or for similar purposes; often, these are agents not falling under more specific ATC subgroups. It is not recognized as a single approved drug but is a placeholder for miscellaneous preparations.
Pharmacokinetics
No pharmacokinetic parameters are reported for 'others' under this ATC code, as it is a group placeholder and not a specific substance; PK data cannot be referenced from the literature.
References
Meng, L, et al., & Holubar, M (2023). Comprehensive guidance for antibiotic dosing in obese adults: 2022 update. Pharmacotherapy 43(3) 226–246. DOI:10.1002/phar.2769 PUBMED:https://pubmed.ncbi.nlm.nih.gov/36703246
Meng, L, et al., & Deresinski, SC (2017). Comprehensive Guidance for Antibiotic Dosing in Obese Adults. Pharmacotherapy 37(11) 1415–1431. DOI:10.1002/phar.2023 PUBMED:https://pubmed.ncbi.nlm.nih.gov/28869666
de la Torre, R, et al., & Camí, J (2004). Human pharmacology of MDMA: pharmacokinetics, metabolism, and disposition. Therapeutic drug monitoring 26(2) 137–144. DOI:10.1097/00007691-200404000-00009 PUBMED:https://pubmed.ncbi.nlm.nih.gov/15228154
Parameters
| Type | Name | Default | Description |
|---|---|---|---|
| Modelica.Units.SI.Mass | weight (from PK_1C) | 75 | patient weight (kg) |
| Modelica.Units.SI.SpecificVolume | VdPerKg (from PK_1C) | 0.9 | Volume of distribution (L/kg) |
| Modelica.Units.SI.MassFraction | F (from PK_1C) | 0.8 | bioavailiability (0-1) |
| Pharmacolibrary.Types.Clearance | Cl (from PK_1C) | 20 | clearance |
| Modelica.Units.SI.Time | adminTime (from PK_1C) | 60 | first administration time (s) |
| Modelica.Units.SI.Time | adminDuration (from PK_1C) | 600 | administration duration (s) |
| Modelica.Units.SI.Time | adminPeriod (from PK_1C) | 8*60*60 | period of administration (default 8 hours)(s) |
| Pharmacolibrary.Types.Mass | adminMass (from PK_1C) | 1000 | administration mass (mg) |
| Integer | adminCount (from PK_1C) | 8 | number of dose administered (1) |
| Pharmacolibrary.Types.Volume | Vd (from PK_1C) | VdPerKg*weight | Volume of distribution (m3) |
| Pharmacolibrary.Types.MassConcentration | Cmin (from PK_1C) | 0.004 | minimal therapeutic range |
| Pharmacolibrary.Types.MassConcentration | Cmax (from PK_1C) | 0.008 | minimal therapeutic range |
| Pharmacolibrary.Types.MassConcentration | Ctox_peak (from PK_1C) | 0.012 | toxicity peak level |
| Pharmacolibrary.Types.MassConcentration | Ctox_trough (from PK_1C) | 0.006 | toxicity trough level |
Connectors
| Type | Name | Default | Description |
|---|---|---|---|
| Types.ConcentrationOutput | C_central (from PK_1C) | ||
| Interfaces.ConcentrationPort_b | centralCPort (from PK_1C) |
Components
| Type | Name | Default | Description |
|---|---|---|---|
| Pharmacokinetic.NoPerfusedTissueCompartment | central (from PK_1C) | ||
| Pharmacokinetic.ClearanceDrivenElimination | elim (from PK_1C) | ||
| Sources.PeriodicDose | periodicDose (from PK_1C) | ||
| Modelica.Units.SI.Time | t1_2 (from PK_1C) | elimination half-life |
Revisions
- 06/2025 Tomas Kulhanek, generated model from data extracted from PUBMED, DrugBank and LLM(GPT4.1)