modelMichaelisMentenDrivenElimination
Extends from Interfaces.InterfaceElimination.
Information
MichaelisMentenDrivenElimination
components represents Michaelis-Menten kinetic in excretion or metabolism.The mass flow rate of excretion is calculated as
Vmax * c
qm = --------
Km + c
where c is concentration of a drug, Vmax is parameter of maximum elimination rate, Km is michaelis constant.
Total excreted mass (MExc) is also calculated.
Parameters
| Type | Name | Default | Description |
|---|---|---|---|
| Modelica.Units.SI.MassFlowRate | Vmax | 1e-3 | Maximum elimination rate (mass/time) |
| Modelica.Units.SI.MassConcentration | Km | 1e-3 | Michaelis constant (mass/volume) |
Connectors
| Type | Name | Default | Description |
|---|---|---|---|
| ConcentrationPort_b | cport (from InterfaceElimination) |
Components
| Type | Name | Default | Description |
|---|---|---|---|
| Types.MassConcentration | C | free concentration of either blood/plasma or tissue at the connector | |
| Types.Mass | MExc | excreted drug mass |